负责人：袁正宏
秘 书：史薇
电 话：021-54237792
传 真：021-64179832
E-mail：sw@fudan.edu.cn
二级学科
1.人体解剖学和组织胚胎学
研究方向：
(1).胚胎干细胞与神经再生;
(2).神经及视觉发育和再生的细胞与分子机制;
(3).生殖细胞发育异常与不孕不育的表观遗传调控;
(4).颅脑形态和功能图像分析; 脑组织样本库建设;
(5).神经干细胞和脑发育;
(6).神经损伤和再生;
(7).肿瘤免疫;
(8).免疫与中枢神经系统可塑性研究
专业领域主要专家：周国民；李文生；秦松；梁春敏；陈红；刘琼等教授。
2. 免疫学
研究方向：
(1). 免疫生物治疗及转化研究；
(2). 肿瘤免疫及自身免疫的分子与细胞基础；
(3). 基于免疫细胞的免疫调控及机理研究；
(4). 区域免疫调节及机制研究；
(5). 感染性疾病发病的免疫学机制；
(6). 病原体免疫逃逸的分子机制。
本专业领域主要专家：储以微、何睿、王继扬、吕鸣芳、张伟娟、严大鹏、徐薇、魏园园等教授。
3.病原生物学
研究方向：
(1).乙型肝炎病毒和丙型肝炎病毒分子生物学与分子免疫学;
(2).微生物基因组结构和功能的研究;
(3).微生物与细胞相互作用及机制的研究;
(4).微生物感染的新型诊断和治疗策略的研究;
(5).针对各类病原体的抗体免疫应答反应; B淋巴细胞中抗体生成的分子机制;
(6).合成免疫学;
(7).病毒持续性感染机理及抗病毒靶标药物;
(8).病毒感染与体液免疫;
(9).肠道微生态与代谢性疾病;
本专业领域内主要专家：闻玉梅（院士）、袁正宏、谢幼华、程训佳、吴健、高谦、王乔、张荣、应天雷、陈捷亮、李建华、吕亮东等教授。
4.病理解剖学
研究方向：
(1). 间质病理, 包括：肾脏病理、肝脏病理及肺脏病理
(2). 肿瘤病理
本专业领域内主要专家：张锦生、许祖德、朱虹光、张志刚、张农等教授。
5.病理生理学：
研究方向：
(1).血管再生修复的调控机制及干预；
(2).心血管重构的分子机制及干预；
(3).干细胞分化心血管细胞的分子机制及应用。
本专业领域内主要专家：孙宁，孟丹，陈思锋，钱睿哲，周平，陈丰原等教授。
6. 药理学
研究方向：
(1).药物成瘾分子和神经机制、学习记忆的环路和分子机制、记忆障碍的发病机制；
(2).神经精神药理学、睡眠与失眠的分子机制、开发镇静催眠药物；
(3).靶向神经系统的脂质体药物设计与体内过程研究；
(4).靶向神经疾病的小分子筛选与溶酶体稳态的调控机制；
(5).神经胶质瘤表观发病机制以及基因药物治疗；
(6).临床药理学：神经胶质细胞的治疗药物靶点；
本专业领域内主要专家：马兰（院士）、黄志力、曲卫敏、占昌友、王菲菲、刘星、魏晓丽、李洋、束敏峰、丁凤菲等教授/研究员。
Basic Medical Sciences
Person in Charge: Prof.Yuan Zhenghong
Secretary: Shi Wei
Tel: (86) 21-54237792
Fax: (86) 21-64179832
E-mail: sw@fudan.edu.cn
1.Human Anatomy and Histo-Embryology
Major Research Projects:
(1).Embryonic stem cells and neurogeneration;
(2).Cellular and molecular mechanisms for neuro and visual development and regeneration;
(3).Epigenetic mechanism in germ cell development and infertility;
(4).Analysis of brain morphology and functional images;
(5).Construction of brain tissue bank;
(6).Neural stem cells and brain development;
(7).Nerve damage and regeneration;
(8).Tumor immunity;
(9).Immunity and plasticity of central nervous system
Experts in this Field: Guomin Zhou, Wensheng Li, Song Qin, Chunmin Liang, Hong Chen, Qiong Liu
2. Immunology
Major Research Projects:
(1). Immunobiotherapy and translational research;
(2). Molecular and cellular basis of tumor immunity and autoimmunity;
(3). Immune regulation and mechanisms of immune cells;
(4). Immune regulation and mechanisms of regional immunity;
(5). Immune mechanisms involved in pathogenesis of infectious diseases;
(6). The molecular mechanisms of the immune evasion of pathogens.
Experts in this Field: Prof. Chu Yiwei, Prof. He Rui, Prof. Wang Jiyang, Prof. Lv Mingfang, Prof. Zhang Weijuan, Prof. Yan Dapeng, Prof. Xu Wei, Prof. Wei Yuanyuan, etc.
3.Medical Microbiology and Medical Parasitology
Major Research Projects:
(1).Molecular Biology and Immunology of HBV, HCV;
(2).Genomic Structure and Related Functions of Microorganisms;
(3).Microorganisms-Host Interactions; Novel Diagnostics and Therapeutic Agents for Microbial Infections; Antibody Immune Response against Various Pathogens;
(4).Molecular Mechanism underlying Antibody Maturation in B Lymphocytes;
(5).Synthetic Immunology;
(6).Viral Persistent Infection and Antiviral Strategy;
(7).Virus infection and humoral immune response;
(8).Gut microbiota and pathogenesis of metabolic diseases
Experts in this Field:Prof. Wen Yumei (Academician), Prof. Yuan Zhenghong, Prof. Xie Youhua, Prof. Chen Xunjia, Prof. Gao Qian, Prof. Wu Jian, Prof. Wang Qiao, Prof. Zhang Rong, Prof. Ying Tianlei, Prof. Chen Jieliang, Prof. Li Jianhua, Prof. Lyu Liangdong.
4.Pathology
Major Research Projects:
Interstitial Pathology (including Renal Pathology, Liver Pathology and Lung Pathology), Tumor Pathology.
Experts in this Field: Prof.Zhang Jingsheng, Prof. Xu Zude, Prof.Zhu Hongguang, Prof.Zhang Zhigang, Prof.Zhang Nong.
5.Pathophysiology:
Major Research Projects:
(1).the regulation mechanism and intervention of vascular regeneration and repair；
(2).the molecular mechanism and intervention of cardiovascular remodeling；
(3).the molecular mechanism and application of stem cell differentiation into cardiovascular cells.
Experts in this Field: Ning Sun, Dan Meng，Sifeng Chen, Ruizhe Qian，Ping Zhou, Alex Chen
6. Pharmacology
Major Research Projects:
(1).Molecular and neurocircuits of drug addiction, learning and memory, memory disorders；
(2).Neuropsychopharmacology, molecular mechanisms of sleep and insomnia, development of sedative and hypnotic drugs;
(3).Development and in vivo delivery mechanisms of liposomal formulations for CNS diseases targeting;
(4).Compound screen and mechanisms of lysosome homeostasis；
(5).Epigenetic mechanisms of glioma pathogenesis and gene therapy;
(6).Explorations of therapeutic drugs and targets in neuroglia cells;
Experts in this Field:Prof. Ma Lan (Academician), Prof. Huang Zhili, Prof. Qu Weimin, Prof. Zhan Changyou, Prof. Wang Feifei, Prof. Liu Xing, Wei Xiaoli, Li Yang, Shu Minfeng, Ding Fengfei.
